Testosterone Deficiency
Testosterone Replacement
Testosterone Deficiency
The disease state of low testosterone is referred to by many different names such as
hypogonadism, andropause and androgen deficiency in the aging male (A.D.A.M.). These terms
are oftentimes used interchangeably and create confusion even amongst healthcare
professionals. All of these terms refer to a condition of low testosterone that is associated with
other symptoms. Some of the signs and symptoms include a decreased sex drive, fatigue,
erectile dysfunction, falling asleep after dinner, memory and concentrating difficulties, bone
density loss and diminished work performance. Oftentimes these symptoms are overlooked or
attributed to some other condition such as normal ageing. Effective therapy for testosterone
deficiency exists.
Why is my testosterone level low?
It is a well known fact that a man's testosterone level begins to decline as early as the age of
thirty (30). In fact, large longitudinal population studies have shown that a man's tetsosterone
decreases by approximately 1% per year after the age of 30. The incidence of low testosterone
has been reported to be around 40% in men over the age of 45. Similar to when a woman goes
through menopause, men go through andropause but at a much slower rate.
Consequently, many of the symptoms associated with this condition can be insidious.
What are some other conditions associated with Hypogonadism?
Certain common conditions are frequently associated with low testosterone. The following table
lists some of these conditions.
Ageing
|
Metabolic Syndrome
|
COPD/Sleep Apnea
|
Obesity
|
Kidney Disease
|
Stress
|
Diabetes Mellitus
|
HIV/AIDS
|
Chronic Infections
|
Chronic Opiod Use
|
Sickle Cell Disease
|
Medications
|
|
Alerting your physician to any of the symptoms asssociated with low testosterone is important. A
health inventory questionnaire called the A.D.A.M questionnaire was designed to identify patients
who potentially might have low testosterone levels. If you answer yes to any three questions or to
any single sexual question, there is a strong possibilty that you have a low testosterone level.
Your physician will order confirmatory lab tests prior to commencing any therapy.
What types of treatment options are available for men with low testosterone
levels?
There are a variety of treatment options available for the man with low testosterone levels.
Currently, there are oral, buccal, transdermal gels, patches, intramuscular injections and
subcutaneous pellets available to treat hypogonadism. Each form of therapy has specific
advantages and disadvantages associated with it. You can discuss with your physician
which form of therapy is right for you.
What are the risks of testosterone replacement therapy?
In general, testosterone replacement therapy is very safe. People oftentimes confuse the
difference between replacing testosterone in the body to return it to normal physiologic
levels with taking testosterone to achieve "super-physiologic" levels for performance
enhancement. These are clearly two different situations. The biggest concerns are related
to prostate health and the development of prostate cancer. Some hypogonadal men might
notice a slight worsening of their urinary symptoms or increase in their PSA. This occurs
because the prostate and PSA are directly controlled by testosterone. Replacing
testosterone into the normal range only increases urinary symptoms and PSA into the range
where they would be if the testosterone level was not low in the first place. Men with
testosterone levels in the normal range (300-1000 ng/dl) are at no greater risk of developing
prostate cancer than their hypogonadal counterparts. Hypogonadism is not only not
protective against prostate cancer, there is some evidence to suggest that hypogonadal
men might develop a more aggressive form of prostate cancer. Men on testosterone
replacement therapy appear to have improved angina-free exercise periods and better
cholesterol profiles than their hypogonadal counterparts. The risks of osteoporosis and
fractures are reduced in men on testosterone replacement therapy.
Watch a video of the Testopel implant procedure for testosterone replacement. The
procedure is performed in 3-4 minutes and replaces testosterone for 3-4 months.